SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
What is the SigProfilerSuite/SigProfilerExtractor GitHub project? Description: "SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting. ". Written in Python. Explain what it does, its main use cases, key features, and who would benefit from using it.
Question is copied to clipboard — paste it after the AI opens.
Clone via HTTPS
Clone via SSH
Download ZIP
Download master.zipReport bugs or request features on the SigProfilerExtractor issue tracker:
Open GitHub Issues