Topic

bioinformatics

Repositories (1488)

jcvi
jcvi tanghaibao Python

Python library to facilitate genome assembly, annotation, and comparative genomics

931
pysam
pysam pysam-developers Cython

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of t...

911
ScienceClaw
ScienceClaw beita6969 TypeScript

🔬🦞 A self-evolving AI research colleague for scientists. 285 skills, zero hallucination, persistent memory.

905
awesome-cheminformatics
awesome-cheminformatics hsiaoyi0504

A curated list of Cheminformatics libraries and software.

887
bwa-mem2
bwa-mem2 bwa-mem2 C++

The next version of bwa-mem

864
wdl
wdl openwdl

Specification for the Workflow Description Language (WDL).

857
plantcv
plantcv danforthcenter Python

Plant phenotyping with image analysis

830
PrimeKG
PrimeKG mims-harvard Jupyter Notebook

Precision Medicine Knowledge Graph (PrimeKG)

829
containers
containers BioContainers Dockerfile

Bioinformatics containers

815
hifiasm
hifiasm chhylp123 C++

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

814
bowtie2
bowtie2 BenLangmead C++

A fast and sensitive gapped read aligner

811
dgl-lifesci
dgl-lifesci awslabs Python

Python package for graph neural networks in chemistry and biology

811
nucleus
nucleus google C++

Python and C++ code for reading and writing genomics data.

803
khmer
khmer dib-lab Python

In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more

789
anndata
anndata scverse Python

Annotated data.

773
deepTools
deepTools deeptools Python

Tools to process and analyze deep sequencing data.

767
PyDESeq2
PyDESeq2 scverse Python

A Python implementation of the DESeq2 pipeline for bulk RNA-seq DEA.

762
vsearch
vsearch torognes C++

Versatile open-source tool for microbiome analysis

761
biopandas
biopandas BioPandas Python

Working with molecular structures in pandas DataFrames

756
poly
poly bebop Go

A Go package for engineering organisms.

737
megahit
megahit voutcn C++

Ultra-fast and memory-efficient (meta-)genome assembler

727
plip
plip pharmai Python

Protein-Ligand Interaction Profiler - Analyze and visualize non-covalent protein-ligand interactions in PDB files according to 📝 Schake, Bolz, et al....

718
seq
seq seq-lang C++

A high-performance, Pythonic language for bioinformatics

707
DnaFeaturesViewer
DnaFeaturesViewer Edinburgh-Genome-Foundry Python

:eye: Python library to plot DNA sequence features (e.g. from Genbank files)

702
bakta
bakta oschwengers Python

Rapid & standardized annotation of bacterial genomes, MAGs & plasmids

682
dash-cytoscape
dash-cytoscape plotly Python

Interactive network visualization in Python and Dash, powered by Cytoscape.js

680
Sniffles
Sniffles fritzsedlazeck Python

Structural variation caller using third generation sequencing

680
ai-research-publications
ai-research-publications aaryansamanta HTML

High-school research portfolio: 2 peer-reviewed publications (IEEE, IJHSR) + 3 active projects spanning quantum-inspired ML, computational biology, bi...

669
ScienceClaw
ScienceClaw AgentTeam-TaichuAI Python

ScienceClaw is a personal research assistant built with LangChain DeepAgents and AIO Sandbox infrastructure, adopting a completely new architecture be...

667
mLLMCelltype
mLLMCelltype cafferychen777 Python

Cell type annotation for single-cell RNA-seq using multi-LLM consensus

662
clinker
clinker gamcil Python

Gene cluster comparison figure generator

654
GraKeL
GraKeL ysig Jupyter Notebook

A scikit-learn compatible library for graph kernels

647
bioawk
bioawk lh3 C

BWK awk modified for biological data

644
biomcp
biomcp genomoncology Rust

BioMCP: Biomedical Model Context Protocol

642
biojava
biojava biojava Java

:book::microscope::coffee: BioJava is an open-source project dedicated to providing a Java library for processing biological data.

632
hh-suite
hh-suite soedinglab C

Remote protein homology detection suite.

628
GTDBTk
GTDBTk Ecogenomics Python

GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.

622
sambamba
sambamba biod D

Tools for working with SAM/BAM data

613
edlib
edlib Martinsos C++

Lightweight, super fast C/C++ (& Python) library for sequence alignment using edit (Levenshtein) distance.

608
cdk
cdk cdk Java

The Chemistry Development Kit

605
sarek
sarek nf-core Nextflow

Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing

604
nanopolish
nanopolish jts C++

Signal-level algorithms for MinION data

603
redun
redun insitro Python

Yet another redundant workflow engine

603
snippy
snippy tseemann Perl

:scissors: :zap: Rapid haploid variant calling and core genome alignment

593
biostar-central
biostar-central ialbert Python

Biostar Q&A

588
cobrapy
cobrapy opencobra Python

COBRApy is a package for constraint-based modeling of metabolic networks.

588
cutadapt
cutadapt marcelm Python

Cutadapt removes adapter sequences from sequencing reads

587
dash-bio
dash-bio plotly Python

Open-source bioinformatics components for Dash

574
dada2
dada2 benjjneb R

Accurate sample inference from amplicon data with single nucleotide resolution

558
sourmash
sourmash sourmash-bio Python

Quickly search, compare, and analyze genomic and metagenomic data sets.

557