Topic

bioinformatics

Repositories (1488)

anvio
anvio merenlab Python

An analysis and visualization platform for 'omics data

535
react-cytoscapejs
react-cytoscapejs plotly JavaScript

React component for Cytoscape.js network visualisations

534
circosJS
circosJS nicgirault JavaScript

d3 library to build circular graphs

531
jvarkit
jvarkit lindenb Java

Java utilities for Bioinformatics

525
awosome-bioinformatics
awosome-bioinformatics openbiox

A curated list of resources for learning bioinformatics.

522
Dash.jl
Dash.jl plotly Julia

Dash for Julia - A Julia interface to the Dash ecosystem for creating analytic web applications in Julia. No JavaScript required.

520
quast
quast ablab AMPL

Genome assembly evaluation tool

520
bioinformatics-one-liners
bioinformatics-one-liners crazyhottommy

Bioinformatics one liners from Ming Tang

504
maftools
maftools PoisonAlien R

Summarize, Analyze and Visualize MAF files from TCGA or in-house studies.

503
juicer
juicer aidenlab Shell

A One-Click System for Analyzing Loop-Resolution Hi-C Experiments

490
pyfaidx
pyfaidx mdshw5 Python

Efficient pythonic random access to fasta subsequences

489
minigraph
minigraph lh3 C

Sequence-to-graph mapper and graph generator

489
PantheonOS
PantheonOS aristoteleo Python

A general, evolvable, and distributed agent framework & harness for data science.

487
tgv
tgv zeqianli Rust

Explore genomes in the terminal. Light, blazing fast 🚀, vim-motion.

483
taxonkit
taxonkit shenwei356 Go

A Practical and Efficient NCBI Taxonomy Toolkit, also supports creating NCBI-style taxdump files for custom taxonomies like GTDB/ICTV

481
GLUE
GLUE gao-lab Python

Graph-linked unified embedding for single-cell multi-omics data integration

480
PostGUI
PostGUI priyank-purohit JavaScript

A React web application to query and share any PostgreSQL database.

478
raxml-ng
raxml-ng amkozlov C

RAxML Next Generation: faster, easier-to-use and more flexible

478
jbrowse
jbrowse GMOD JavaScript

JBrowse 1, a full-featured genome browser built with JavaScript and HTML5. For JBrowse 2, see https://github.com/GMOD/jbrowse-components.

474
hap.py
hap.py Illumina C++

Haplotype VCF comparison tools

473
awesome-bioie
awesome-bioie caufieldjh

🧫 A curated list of resources relevant to doing Biomedical Information Extraction (including BioNLP)

468
manta
manta Illumina C++

Structural variant and indel caller for mapped sequencing data

467
Bismark
Bismark FelixKrueger Rust

A tool to map bisulfite converted sequence reads and determine cytosine methylation states

466
histolab
histolab histolab Python

Library for Digital Pathology Image Processing

465
seqan3
seqan3 seqan C++

The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.

463
p2rank
p2rank rdk Groovy

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

461
RNAseq-workflow
RNAseq-workflow twbattaglia R

A repository for setting up a RNAseq workflow

461
weekly
weekly openbiox HTML

生信爱好者周刊(每周日发布)

460
awesome-biology
awesome-biology raivivek

Curated (meta)list of resources for Biology.

459
pdb-tools
pdb-tools haddocking Python

A dependency-free cross-platform swiss army knife for PDB files.

457
Deep_learning_examples
Deep_learning_examples liyu95 Jupyter Notebook

Examples of using deep learning in Bioinformatics

456
cellrank
cellrank scverse Python

CellRank: dynamics from multi-view single-cell data

456
multiPrime
multiPrime joybio Python

multiPrime is a mismatch-tolerant minimal primer set design tool for large and diverse sequences (e.g. Virus). Here is a web-based version (test: http...

456
craftgrn
craftgrn oncologylab R

Combined RNA and ATAC Footprint Training of Gene Regulatory Network

453
cyvcf2
cyvcf2 brentp Cython

cython + htslib == fast VCF and BCF processing

449
fp-tools
fp-tools oncologylab Python

Command-first ATAC-seq footprinting, motif analysis, and reproducible interactive reports

447
single-cell-pseudotime
single-cell-pseudotime agitter

An overview of algorithms for estimating pseudotime in single-cell RNA-seq data

444
signac
signac stuart-lab R

R toolkit for the analysis of single-cell chromatin data

428
SURVIVOR
SURVIVOR fritzsedlazeck C++

Toolset for SV simulation, comparison and filtering

426
pyGenomeViz
pyGenomeViz moshi4 Python

A genome visualization python package for comparative genomics

424
truvari
truvari ACEnglish Python

Structural variant toolkit for VCFs

423
arvados
arvados arvados Go

An open source platform for managing and analyzing biomedical big data

420
miniprot
miniprot lh3 C

Align proteins to genomes with splicing and frameshift

420
BioClaw
BioClaw Runchuan-BU TypeScript

AI-Powered Bioinformatics Research Assistant. Built on OpenClaw.

410
lightdock
lightdock lightdock Python

Protein-protein, protein-peptide and protein-DNA docking framework based on the GSO algorithm

409
PyComplexHeatmap
PyComplexHeatmap DingWB Python

PyComplexHeatmap: A Python package to plot complex heatmap (clustermap)

406
BioReason
BioReason bowang-lab Jupyter Notebook

BioReason: Incentivizing Multimodal Biological Reasoning within a DNA-LLM Model | NeurIPS '25

406
vcfanno
vcfanno brentp Go

annotate a VCF with other VCFs/BEDs/tabixed files

403
mixcr
mixcr milaboratory Kotlin

MiXCR is an ultimate software platform for analysis of Next-Generation Sequencing (NGS) data for immune profiling.

403
AllenSDK
AllenSDK AllenInstitute Jupyter Notebook

code for reading and processing Allen Institute for Brain Science data

398